Mar 31, 2026 filings. Quarterly 13F reports arrive up to 45 days after quarter end; this register is filed through May 29, 2026.
370 institutional managers reported holding CPRX for the quarter ended Mar 31, 2026. Together they hold about 82% of shares outstanding; the top 10 hold 45%. 48 opened new positions; 50 closed out. Complete ranked register from SEC 13F filings.
| manager | shares | % out | value (Mar 31, 2026 close) | change | held since |
|---|---|---|---|---|---|
| BlackRock | 18.77M | 14.79% | $465.1M | added +0.8% | 2014 Q2 |
| Vanguard Group | 8.56M | 6.75% | $212.2M | added +1.6% | ≤2013 |
| State Street | 6.86M | 5.41% | $170.0M | trimmed -0.6% | 2014 Q1 |
| American Century Companies INC | 4.14M | 3.26% | $102.5M | added +36.8% | 2020 Q2 |
| Deerfield Management Company, L.p. | 3.94M | 3.11% | $97.7M | trimmed -19.7% | 2022 Q3 |
| Dimensional Fund Advisors | 3.43M | 2.70% | $85.0M | added +14.5% | 2018 Q3 |
| Bank OF America CORP /DE/ | 3.04M | 2.39% | $75.2M | added +38% | ≤2013 |
| Geode Capital | 2.97M | 2.34% | $73.6M | added +2.5% | ≤2013 |
| Morgan Stanley | 2.69M | 2.12% | $66.6M | trimmed -8.4% | 2013 Q4 |
| Renaissance Technologies | 2.35M | 1.85% | $58.2M | trimmed -11.4% | 2021 Q3 |
| Royce & Associates | 2.09M | 1.65% | $51.8M | added +9.4% | 2019 Q4 |
| Janus Henderson | 2.00M | 1.57% | $49.5M | added +16.2% | 2021 Q2 |
| Boston Partners | 1.71M | 1.35% | $42.4M | added +39% | 2022 Q1 |
| Charles Schwab Investment Management | 1.43M | 1.13% | $35.4M | added +5.4% | 2017 Q2 |
| UBS | 1.27M | 1.00% | $31.4M | added +36.5% | 2017 Q2 |
| Northern Trust | 1.24M | 0.97% | $30.7M | added +2.1% | ≤2013 |
| Kennedy Capital Management LLC | 1.20M | 0.94% | $29.7M | trimmed -0.8% | 2023 Q2 |
| Goldman Sachs | 984.7k | 0.78% | $24.4M | added +0.5% | 2014 Q3 |
| Arrowstreet Capital | 955.3k | 0.75% | $23.7M | trimmed -40.9% | 2023 Q1 |
| Raymond James Financial INC | 889.9k | 0.70% | $22.0M | added +5.7% | 2016 Q1 |
| Victory Capital Management INC | 866.6k | 0.68% | $21.5M | trimmed -2% | 2019 Q3 |
| Susquehanna International Group | 852.8k | 0.67% | $21.1M | added +419.3% | 2017 Q4 |
| Fundsmith (focused) | 844.9k | 0.67% | $20.9M | trimmed -74.9% | 2025 Q1 |
| Oberweis Asset Management INC/ | 780.6k | 0.61% | $19.3M | added +33% | 2022 Q4 |
| T. Rowe Price | 773.4k | 0.61% | $19.2M | added +3.3% | 2022 Q3 |
| Millennium Management | 767.0k | 0.60% | $19.0M | trimmed -22.8% | 2019 Q3 |
| Invesco | 752.8k | 0.59% | $18.7M | trimmed -41.8% | 2019 Q3 |
| Nomura Asset Management International INC. | 748.1k | 0.59% | $18.5M | trimmed -3.9% | 2025 Q1 |
| Systematic Financial Management LP | 747.5k | 0.59% | $18.5M | added +3.4% | 2025 Q1 |
| Federated Hermes, INC. | 740.3k | 0.58% | $18.3M | added +11.5% | 2019 Q2 |
| BNY Mellon | 682.3k | 0.54% | $16.9M | trimmed -2.6% | 2013 Q3 |
| Principal Financial Group INC | 676.0k | 0.53% | $16.7M | trimmed -1.1% | 2017 Q2 |
| Swedbank Robur | 616.1k | 0.49% | $15.3M | unchanged | 2025 Q2 |
| LSV Asset Management | 609.5k | 0.48% | $15.1M | added +12.9% | 2020 Q2 |
| Voya Investment Management LLC | 589.9k | 0.47% | $14.6M | added +4% | 2017 Q2 |
| Citadel Advisors | 581.1k | 0.46% | $14.4M | added +88.4% | 2017 Q2 |
| Clark Capital Management Group, INC. | 568.7k | 0.45% | $14.1M | opened | 2026 Q1 |
| Glenmede Trust CO NA | 565.4k | 0.45% | $14.0M | trimmed -8.5% | 2021 Q3 |
| IMC-Chicago, LLC | 563.7k | 0.44% | $14.0M | opened | 2026 Q1 |
| Jane Street | 545.2k | 0.43% | $13.5M | added +104.8% | 2020 Q2 |
| Public Sector Pension Investment Board | 526.3k | 0.41% | $13.0M | added +6.8% | 2022 Q3 |
| William Blair Investment Management, LLC | 479.0k | 0.38% | $11.9M | opened | 2026 Q1 |
| Globeflex Capital L P | 450.6k | 0.35% | $11.2M | added +54.2% | 2020 Q4 |
| Renaissance Group LLC | 445.2k | 0.35% | $11.0M | added +28.5% | 2024 Q4 |
| Point72 | 425.9k | 0.34% | $10.6M | opened | 2026 Q1 |
| Gables Capital Management INC. | 424.6k | 0.34% | $10.5M | unchanged | 2018 Q1 |
| Nuveen | 419.5k | 0.33% | $10.4M | unchanged | 2019 Q2 |
| Franklin Resources | 416.7k | 0.33% | $10.3M | added +170.7% | 2022 Q1 |
| Qube Research & Technologies LTD | 412.7k | 0.33% | $10.2M | trimmed -15.3% | 2023 Q3 |
| JW Asset Management, LLC (focused) | 388.4k | 0.31% | $9.6M | unchanged | 2022 Q4 |
Largest 50 of 370 shown; the full ranked, searchable register is at boothcheck.com/holders/CPRX. Related filers are grouped using the filings' own included-manager declarations. Historically, several managers opening new positions in the same quarter said almost nothing about the quarter that followed (59,118 cases since 2013). A filed record, not a forecast. Nothing here is investment advice.