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APLS

APELLIS PHARMACEUTICALS, INC.

At today's price, APELLIS PHARMACEUTICALS, INC. (APLS) is priced for +37.6% growth. boothcheck doesn't publish a fair value or a price target; it shows what the price assumes, so you can judge whether that bar is too high. Built from SEC EDGAR filings.

Live priced in
+37.6% growth
Priced In
extreme

Key Takeaways

• Apellis sells two complement-system drugs, SYFOVRE for the eye disease geographic atrophy and EMPAVELI for rare blood and kidney disorders, and total revenue rose to $268.3 million in the most recent quarter from $166.8 million a year earlier. [Source: Q1 2026 10-Q, May 7 2026] • The defining risk is competition in geographic atrophy, where Astellas' IZERVAY is the direct rival to SYFOVRE and recently won an FDA label update that lets it dose beyond twelve months. [Source: FDA label update, 20

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Institutional ownership

308 institutional managers reported holding APLS in 13F filings for the quarter ended 2026-03-31. 114 opened new positions that quarter. Held by BlackRock, Vanguard Group, Morgan Stanley, among others.

Quarterly 13F filings arrive up to 45 days after quarter end, so the picture is never current (filed through 2026-05-29). Nothing here is investment advice.

Capital returns

APLS's share count grew 57.1% over the past five years. It pays no dividend.

Share counts are split-adjusted; repurchase totals are gross of share issuance. Nothing here is investment advice.

Insider activity

No open-market insider buys on file at APLS over the trailing three years. Absence is a fact about the company, not a signal. 21 officers and directors are on file.

Code P open-market purchases from SEC Form 4 filings, non-derivative, excluding scheduled 10b5-1 plans. Nothing here is investment advice.

Earnings reactions

APLS's recent reports: the day-one move, then what the following quarter actually did.

reportday onenext quarter
2021-02-26-7.9%+5.2%
2021-08-10-3.7%-43.8%
2022-03-01-6.1%-0.3%
2022-08-09+3.8%-10.6%

Day-one is the close-to-close move around the filing. Nothing here is investment advice.

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Last analyzed: June 27, 2026

For informational and research purposes only. Not investment advice. Not a recommendation to buy, sell, or hold any security. boothcheck is not a registered investment adviser. Past performance does not guarantee future results.