Mar 31, 2026 filings. Quarterly 13F reports arrive up to 45 days after quarter end; this register is filed through May 29, 2026.
195 institutional managers reported holding PGEN for the quarter ended Mar 31, 2026. Together they hold about 38% of shares outstanding; the top 10 hold 25%. 41 opened new positions; 19 closed out. Complete ranked register from SEC 13F filings.
| manager | shares | % out | value (Mar 31, 2026 close) | change | held since |
|---|---|---|---|---|---|
| Patient Capital Management, LLC (focused) | 17.82M | 5.03% | $68.8M | trimmed -4.6% | 2021 Q4 |
| BlackRock | 15.22M | 4.30% | $58.8M | added +0.9% | 2020 Q1 |
| State Street | 10.89M | 3.07% | $42.0M | added +0.6% | 2020 Q1 |
| Vanguard Group | 10.77M | 3.04% | $41.6M | added +2.5% | 2020 Q1 |
| Diametric Capital, LP | 6.80M | 1.92% | $26.3M | added +76.8% | 2025 Q2 |
| Point72 | 6.64M | 1.88% | $25.6M | trimmed -51.6% | 2025 Q3 |
| Tang Capital Management LLC | 6.42M | 1.81% | $24.8M | added +14.2% | 2025 Q3 |
| Geode Capital | 4.61M | 1.30% | $17.8M | added +3.4% | 2020 Q1 |
| Occam Crest Management LP (focused) | 4.27M | 1.21% | $16.5M | added +21.9% | 2025 Q3 |
| Iridian Asset Management LLC/CT (focused) | 3.59M | 1.01% | $13.9M | unchanged | 2020 Q1 |
| Boxer Capital Management, LLC | 3.50M | 0.99% | $13.5M | added +154.5% | 2025 Q3 |
| Goldman Sachs | 3.35M | 0.95% | $12.9M | added +54.1% | 2020 Q1 |
| Citadel Advisors | 2.70M | 0.76% | $10.4M | trimmed -16.8% | 2025 Q2 |
| Franklin Resources | 2.63M | 0.74% | $10.2M | added +462.7% | 2021 Q4 |
| Morgan Stanley | 2.41M | 0.68% | $9.3M | trimmed -24.4% | 2020 Q1 |
| FMR (Fidelity) | 2.00M | 0.56% | $7.7M | trimmed -57% | 2021 Q2 |
| Jane Street | 1.82M | 0.51% | $7.0M | opened | 2023 Q1 |
| Northern Trust | 1.61M | 0.46% | $6.2M | added +2.1% | 2020 Q1 |
| Bank OF America CORP /DE/ | 1.47M | 0.41% | $5.7M | trimmed -32.8% | 2020 Q1 |
| Charles Schwab Investment Management | 1.46M | 0.41% | $5.6M | trimmed -3.1% | 2020 Q1 |
| Woodline Partners LP | 1.40M | 0.40% | $5.4M | unchanged | 2025 Q4 |
| Prelude Capital Management, LLC | 1.27M | 0.36% | $4.9M | added +95.4% | 2025 Q2 |
| UBS | 1.04M | 0.29% | $4.0M | trimmed -7.5% | 2020 Q1 |
| Corient Private Wealth LLC | 911.2k | 0.26% | $3.5M | added +111.1% | 2024 Q3 |
| Adage Capital Partners GP, L.l.c. | 846.0k | 0.24% | $3.3M | unchanged | 2024 Q3 |
| Driehaus Capital Management LLC | 793.8k | 0.22% | $3.1M | trimmed -78% | 2025 Q3 |
| HRT Financial LP | 710.8k | 0.20% | $2.7M | opened | 2026 Q1 |
| LexAurum Advisors, LLC | 689.4k | 0.20% | $2.7M | opened | 2022 Q1 |
| GMT Capital CORP | 668.8k | 0.19% | $2.6M | opened | 2024 Q2 |
| Lansing Street Advisors | 553.7k | 0.16% | $2.1M | added +1.2% | 2025 Q3 |
| Nuveen | 534.0k | 0.15% | $2.1M | added +1% | 2020 Q1 |
| Wellington Management | 508.4k | 0.14% | $2.0M | added +5.3% | 2025 Q3 |
| Barclays PLC | 491.7k | 0.14% | $1.9M | trimmed -43.2% | 2022 Q1 |
| BNY Mellon | 433.3k | 0.12% | $1.7M | trimmed -7.6% | 2020 Q1 |
| Susquehanna International Group | 432.7k | 0.12% | $1.7M | trimmed -15.8% | 2020 Q1 |
| GLR Partners, LLC | 412.0k | 0.12% | $1.6M | opened | 2026 Q1 |
| Arrowstreet Capital | 395.7k | 0.11% | $1.5M | opened | 2026 Q1 |
| Citigroup INC | 381.4k | 0.11% | $1.5M | added +229.6% | 2020 Q1 |
| Cetera Investment Advisers | 374.5k | 0.11% | $1.4M | added +0.9% | 2021 Q3 |
| Swiss National Bank | 349.0k | 0.10% | $1.3M | unchanged | 2025 Q4 |
| KBC Group NV | 345.8k | 0.10% | $1.3M | opened | 2026 Q1 |
| ExodusPoint | 344.3k | 0.10% | $1.3M | opened | 2026 Q1 |
| Rafferty Asset Management, LLC | 319.2k | 0.09% | $1.2M | trimmed -14.7% | 2025 Q3 |
| Caption Management, LLC | 306.6k | 0.09% | $1.2M | opened | 2026 Q1 |
| Cibc Bancorp USA INC. | 302.0k | 0.09% | $1.2M | added +5.4% | 2023 Q3 |
| Voleon Capital Management LP | 274.9k | 0.08% | $1.1M | trimmed -40.9% | 2025 Q3 |
| Osaic Holdings, INC. | 222.4k | 0.06% | $858k | added +1.3% | 2020 Q1 |
| LPL Financial LLC | 211.1k | 0.06% | $815k | added +3.2% | 2020 Q1 |
| AllianceBernstein | 206.1k | 0.06% | $796k | unchanged | 2020 Q1 |
| Victory Capital Management INC | 202.7k | 0.06% | $782k | trimmed -14.3% | 2020 Q1 |
Largest 50 of 195 shown; the full ranked, searchable register is at boothcheck.com/holders/PGEN. Related filers are grouped using the filings' own included-manager declarations. Historically, several managers opening new positions in the same quarter said almost nothing about the quarter that followed (59,118 cases since 2013). A filed record, not a forecast. Nothing here is investment advice.