Mar 31, 2026 filings. Quarterly 13F reports arrive up to 45 days after quarter end; this register is filed through May 29, 2026.
673 institutional managers reported holding NBIX for the quarter ended Mar 31, 2026. Together they hold about 91% of shares outstanding; the top 10 hold 48%. 79 opened new positions; 117 closed out. Complete ranked register from SEC 13F filings.
| manager | shares | % out | value (Mar 31, 2026 close) | change | held since |
|---|---|---|---|---|---|
| BlackRock | 13.39M | 12.95% | $1.76B | added +4.3% | ≤2013 |
| Vanguard Group | 10.02M | 9.69% | $1.32B | added +3.2% | ≤2013 |
| Dodge & Cox | 5.46M | 5.28% | $719.4M | trimmed -0.9% | 2023 Q3 |
| AQR Capital | 4.94M | 4.78% | $650.6M | added +51% | ≤2013 |
| State Street | 4.35M | 4.21% | $573.6M | added +2.6% | ≤2013 |
| Two Sigma | 3.06M | 2.96% | $403.2M | added +210.8% | 2021 Q4 |
| Renaissance Technologies | 2.42M | 2.34% | $318.6M | added +8% | 2017 Q4 |
| Geode Capital | 2.14M | 2.07% | $281.5M | added +3.8% | ≤2013 |
| UBS | 1.79M | 1.73% | $236.2M | added +5.1% | ≤2013 |
| BNP Paribas Financial Markets | 1.73M | 1.67% | $227.5M | added +7.3% | ≤2013 |
| Wellington Management | 1.39M | 1.34% | $183.0M | trimmed -20.4% | ≤2013 |
| Vestal Point Capital, LP | 1.25M | 1.21% | $164.7M | opened | 2026 Q1 |
| Millennium Management | 1.25M | 1.21% | $164.3M | added +181.7% | 2017 Q3 |
| Northern Trust | 1.24M | 1.20% | $163.7M | added +1.8% | ≤2013 |
| Morgan Stanley | 1.22M | 1.18% | $160.6M | added +0.8% | ≤2013 |
| RTW Investments, LP | 1.06M | 1.03% | $139.9M | unchanged | 2025 Q2 |
| First Trust Advisors LP | 959.2k | 0.93% | $126.4M | added +97% | 2016 Q1 |
| Charles Schwab Investment Management | 902.8k | 0.87% | $118.9M | added +6.1% | ≤2013 |
| IEQ Capital, LLC | 766.0k | 0.74% | $100.9M | added +2.8% | 2023 Q2 |
| Victory Capital Management INC | 731.6k | 0.71% | $96.4M | added +487.4% | 2015 Q2 |
| Armistice Capital, LLC | 724.0k | 0.70% | $95.4M | trimmed -11.7% | 2022 Q1 |
| Dimensional Fund Advisors | 711.8k | 0.69% | $93.8M | trimmed -0.7% | 2015 Q1 |
| BNY Mellon | 702.5k | 0.68% | $92.5M | trimmed -4.9% | ≤2013 |
| Braidwell LP | 652.1k | 0.63% | $85.9M | trimmed -13.2% | 2023 Q1 |
| Fiera Capital CORP | 651.3k | 0.63% | $85.8M | added +2.2% | 2020 Q3 |
| Franklin Resources | 611.3k | 0.59% | $80.5M | added +14.7% | ≤2013 |
| Deerfield Management Company, L.p. | 610.0k | 0.59% | $80.4M | trimmed -48.5% | 2021 Q1 |
| Pictet Asset Management Holding SA | 602.6k | 0.58% | $79.4M | trimmed -22.4% | 2015 Q3 |
| Raymond James Financial INC | 601.5k | 0.58% | $79.2M | trimmed -4.7% | 2015 Q4 |
| Gw&k Investment Management, LLC | 593.7k | 0.57% | $78.2M | added +3% | 2016 Q1 |
| Bank OF America CORP /DE/ | 583.8k | 0.56% | $76.9M | added +10.6% | ≤2013 |
| Swedbank Robur | 579.4k | 0.56% | $76.3M | trimmed -0.8% | 2021 Q1 |
| AllianceBernstein | 523.5k | 0.51% | $69.0M | trimmed -5.8% | ≤2013 |
| Jacobs Levy Equity Management, INC | 520.3k | 0.50% | $68.5M | added +1389.6% | 2022 Q3 |
| Ameriprise Financial INC | 512.0k | 0.49% | $67.5M | trimmed -12.6% | 2017 Q3 |
| Marshall Wace | 509.0k | 0.49% | $67.0M | added +45.9% | 2024 Q4 |
| PRIMECAP Management | 496.3k | 0.48% | $65.4M | trimmed -2.2% | 2022 Q4 |
| Squarepoint Ops LLC | 488.0k | 0.47% | $64.3M | added +132.7% | 2025 Q2 |
| Janus Henderson | 467.0k | 0.45% | $61.5M | added +1.7% | 2013 Q3 |
| Nuveen | 443.1k | 0.43% | $58.4M | added +54.5% | 2019 Q2 |
| Man Group | 415.9k | 0.40% | $54.8M | added +79.9% | 2021 Q4 |
| Hood River Capital Management LLC | 404.4k | 0.39% | $53.3M | added +3.9% | 2021 Q3 |
| Hudson Bay Capital | 395.9k | 0.38% | $52.1M | added +29.8% | 2020 Q1 |
| Legal & General Group PLC | 380.6k | 0.37% | $50.1M | added +15.1% | 2014 Q3 |
| Deutsche Bank AG\ | 365.3k | 0.35% | $48.1M | trimmed -0.7% | ≤2013 |
| Gotham Asset Management | 360.1k | 0.35% | $47.4M | added +113.6% | 2021 Q4 |
| Invesco | 356.0k | 0.34% | $46.9M | added +3.7% | ≤2013 |
| Acadian Asset Management | 350.7k | 0.34% | $46.2M | added +40.8% | 2022 Q1 |
| Goldman Sachs | 349.2k | 0.34% | $46.0M | trimmed -4.2% | ≤2013 |
| Allspring Global Investments Holdings, LLC | 332.4k | 0.32% | $43.8M | trimmed -2.1% | 2021 Q4 |
Largest 50 of 673 shown; the full ranked, searchable register is at boothcheck.com/holders/NBIX. Related filers are grouped using the filings' own included-manager declarations. Historically, several managers opening new positions in the same quarter said almost nothing about the quarter that followed (59,118 cases since 2013). A filed record, not a forecast. Nothing here is investment advice.