Mar 31, 2026 filings. Quarterly 13F reports arrive up to 45 days after quarter end; this register is filed through May 29, 2026.
158 institutional managers reported holding CNTA for the quarter ended Mar 31, 2026. Reported positions total over 95% of shares outstanding; the top 10 hold 56%. 46 opened new positions; 34 closed out. Complete ranked register from SEC 13F filings.
| manager | shares | % out | value (Mar 31, 2026 close) | change | held since |
|---|---|---|---|---|---|
| Medicxi Ventures Management (Jersey) LTD (focused) | 19.96M | 13.00% | $792.1M | unchanged | 2021 Q2 |
| Avoro Capital Advisors LLC (focused) | 11.43M | 7.44% | $453.6M | trimmed -21.5% | 2025 Q1 |
| Index Venture Life Associates VI LTD (focused) | 9.96M | 6.49% | $395.3M | unchanged | 2024 Q4 |
| Adage Capital Partners GP, L.l.c. | 8.93M | 5.81% | $354.1M | trimmed -20.9% | 2023 Q2 |
| Pentwater Capital Management LP | 8.17M | 5.32% | $324.2M | opened | 2026 Q1 |
| FMR (Fidelity) | 6.85M | 4.46% | $271.9M | trimmed -23.5% | 2021 Q2 |
| EcoR1 Capital, LLC (focused) | 6.00M | 3.91% | $238.1M | added +92.6% | 2025 Q3 |
| Perceptive Advisors LLC | 5.26M | 3.42% | $208.7M | added +80.2% | 2024 Q1 |
| Capital Group (American Funds) | 4.83M | 3.15% | $191.8M | added +317.1% | 2025 Q2 |
| Farallon Capital | 4.81M | 3.13% | $190.8M | trimmed -10.6% | 2024 Q1 |
| TCG Crossover Management, LLC (focused) | 4.29M | 2.79% | $170.1M | unchanged | 2023 Q3 |
| Morgan Stanley | 4.27M | 2.78% | $169.4M | added +284.8% | 2021 Q3 |
| Paradigm Biocapital Advisors LP (focused) | 3.57M | 2.33% | $141.8M | opened | 2026 Q1 |
| Janus Henderson | 3.49M | 2.27% | $138.6M | trimmed -14.7% | 2024 Q3 |
| Deep Track Capital, LP | 3.16M | 2.06% | $125.3M | added +57.9% | 2024 Q3 |
| Logos Global Management LP | 2.13M | 1.38% | $84.3M | added +962.5% | 2025 Q3 |
| RTW Investments, LP | 2.05M | 1.34% | $81.5M | added +14.7% | 2024 Q3 |
| Federated Hermes, INC. | 2.05M | 1.33% | $81.3M | trimmed -12.5% | 2025 Q3 |
| Braidwell LP | 1.99M | 1.29% | $78.8M | trimmed -9.2% | 2025 Q4 |
| Bank OF America CORP /DE/ | 1.93M | 1.26% | $76.7M | added +103.5% | 2021 Q2 |
| Maverick Capital | 1.85M | 1.21% | $73.6M | added +12.8% | 2025 Q4 |
| First Light Asset Management, LLC (focused) | 1.56M | 1.02% | $61.9M | trimmed -31.5% | 2024 Q1 |
| Affinity Asset Advisors, LLC | 1.40M | 0.91% | $55.6M | added +133.1% | 2021 Q2 |
| Foresite Capital Management VI LLC (focused) | 1.36M | 0.89% | $54.1M | unchanged | 2024 Q4 |
| General Atlantic, L.p. (focused) | 1.35M | 0.88% | $53.8M | trimmed -77.9% | 2021 Q2 |
| Goldman Sachs | 1.14M | 0.74% | $45.4M | added +46.9% | 2022 Q2 |
| Siren, L.l.c. | 1.05M | 0.69% | $41.8M | trimmed -73.8% | 2024 Q3 |
| Cormorant Asset Management, LP (focused) | 1.05M | 0.68% | $41.7M | trimmed -20.8% | 2021 Q2 |
| Alpine Associates Management INC. | 865.5k | 0.56% | $34.3M | opened | 2026 Q1 |
| Woodline Partners LP | 859.1k | 0.56% | $34.1M | added +48.6% | 2021 Q2 |
| Balyasny Asset Management | 852.8k | 0.56% | $33.8M | added +81.9% | 2024 Q1 |
| Octagon Capital Advisors LP (focused) | 750.0k | 0.49% | $29.8M | unchanged | 2023 Q1 |
| Millennium Management | 722.1k | 0.47% | $28.7M | trimmed -61.4% | 2023 Q4 |
| BNP Paribas Financial Markets | 704.7k | 0.46% | $28.0M | added +28711.8% | 2024 Q4 |
| American Century Companies INC | 687.4k | 0.45% | $27.3M | trimmed -39.2% | 2021 Q2 |
| Franklin Resources | 684.5k | 0.45% | $27.2M | trimmed -71.1% | 2021 Q2 |
| Baker Bros. Advisors LP | 670.8k | 0.44% | $26.6M | unchanged | 2025 Q4 |
| Eventide Asset Management, LLC | 668.1k | 0.43% | $26.5M | opened | 2026 Q1 |
| Toronto Dominion Bank | 654.9k | 0.43% | $26.0M | opened | 2026 Q1 |
| TIG Advisors, LLC | 648.3k | 0.42% | $25.7M | opened | 2026 Q1 |
| D. E. Shaw | 643.8k | 0.42% | $25.5M | trimmed -22.6% | 2025 Q2 |
| Bain Capital Life Sciences Investors, LLC (focused) | 635.0k | 0.41% | $25.2M | opened | 2026 Q1 |
| Qube Research & Technologies LTD | 628.0k | 0.41% | $24.9M | added +65.8% | 2023 Q3 |
| BlackRock | 625.4k | 0.41% | $24.8M | added +5.5% | 2021 Q2 |
| Citadel Advisors | 598.2k | 0.39% | $23.7M | added +15% | 2021 Q2 |
| 5AM Venture Management, LLC (focused) | 580.9k | 0.38% | $23.1M | unchanged | 2024 Q1 |
| PFM Health Sciences, LP | 528.2k | 0.34% | $21.0M | trimmed -10.7% | 2024 Q1 |
| Weiss Asset Management LP | 510.4k | 0.33% | $20.3M | opened | 2026 Q1 |
| Spruce Street Capital LP (focused) | 489.8k | 0.32% | $19.4M | added +528% | 2025 Q4 |
| Silverarc Capital Management, LLC | 466.3k | 0.30% | $18.5M | added +1.8% | 2024 Q3 |
Largest 50 of 158 shown; the full ranked, searchable register is at boothcheck.com/holders/CNTA. Related filers are grouped using the filings' own included-manager declarations. Historically, several managers opening new positions in the same quarter said almost nothing about the quarter that followed (59,118 cases since 2013). A filed record, not a forecast. Nothing here is investment advice.