Mar 31, 2026 filings. Quarterly 13F reports arrive up to 45 days after quarter end; this register is filed through May 29, 2026.
169 institutional managers reported holding CAPR for the quarter ended Mar 31, 2026. Together they hold about 58% of shares outstanding; the top 10 hold 36%. 64 opened new positions; 26 closed out. Complete ranked register from SEC 13F filings.
| manager | shares | % out | value (Mar 31, 2026 close) | change | held since |
|---|---|---|---|---|---|
| Suvretta Capital Management, LLC | 3.82M | 6.65% | $116.0M | added +113.9% | 2025 Q4 |
| BlackRock | 3.42M | 5.96% | $104.0M | added +20% | 2015 Q2 |
| Tang Capital Management LLC | 3.40M | 5.92% | $103.3M | added +100% | 2025 Q4 |
| Vanguard Group | 2.80M | 4.87% | $85.0M | added +9.2% | 2015 Q2 |
| State Street | 2.18M | 3.80% | $66.3M | added +163% | 2021 Q2 |
| RA Capital Management, L.p. | 1.51M | 2.63% | $45.8M | unchanged | 2025 Q4 |
| Geode Capital | 1.12M | 1.95% | $34.0M | added +9.9% | 2015 Q2 |
| Goldman Sachs | 912.0k | 1.59% | $27.7M | added +103.6% | 2021 Q3 |
| Jones Hill Capital LP (focused) | 909.2k | 1.58% | $27.6M | opened | 2026 Q1 |
| Point72 | 821.2k | 1.43% | $25.0M | trimmed -55.4% | 2025 Q3 |
| FMR (Fidelity) | 772.6k | 1.34% | $23.5M | trimmed -16.3% | 2024 Q1 |
| Boxer Capital Management, LLC | 590.0k | 1.03% | $17.9M | added +81.5% | 2025 Q4 |
| Jane Street | 566.1k | 0.99% | $17.2M | opened | 2025 Q3 |
| J. Goldman & CO LP | 541.5k | 0.94% | $16.5M | trimmed -9% | 2025 Q3 |
| Citadel Advisors | 539.2k | 0.94% | $16.4M | trimmed -40.2% | 2019 Q4 |
| Ikarian Capital, LLC | 528.0k | 0.92% | $16.0M | trimmed -8.7% | 2025 Q3 |
| UBS | 448.4k | 0.78% | $13.6M | added +88% | 2024 Q1 |
| Morgan Stanley | 423.8k | 0.74% | $12.9M | trimmed -27.7% | 2019 Q2 |
| Northern Trust | 417.5k | 0.73% | $12.7M | added +19.1% | 2020 Q2 |
| Bank OF America CORP /DE/ | 415.5k | 0.72% | $12.6M | added +672% | 2022 Q2 |
| Mercer Global Advisors INC /ADV | 403.0k | 0.70% | $12.2M | opened | 2026 Q1 |
| DG Capital Management, LLC (focused) | 392.1k | 0.68% | $11.9M | trimmed -5.3% | 2025 Q3 |
| Millennium Management | 356.4k | 0.62% | $10.8M | trimmed -47.8% | 2023 Q3 |
| Barclays PLC | 314.8k | 0.55% | $9.6M | added +163.7% | 2024 Q2 |
| Balyasny Asset Management | 297.1k | 0.52% | $9.0M | trimmed -15.8% | 2025 Q4 |
| RTW Investments, LP | 250.0k | 0.43% | $7.6M | unchanged | 2025 Q4 |
| Palo Alto Investors LP | 229.8k | 0.40% | $7.0M | added +1.5% | 2025 Q4 |
| Moody Aldrich Partners LLC | 226.0k | 0.39% | $6.9M | added +8.3% | 2025 Q4 |
| Trexquant Investment LP | 222.4k | 0.39% | $6.8M | opened | 2026 Q1 |
| HBK Sorce Advisory LLC | 204.8k | 0.36% | $6.2M | added +0.6% | 2025 Q1 |
| Integral Health Asset Management, LLC | 200.0k | 0.35% | $6.1M | opened | 2026 Q1 |
| Raymond James Financial INC | 196.3k | 0.34% | $6.0M | unchanged | 2025 Q1 |
| Invesco | 185.4k | 0.32% | $5.6M | added +1260.9% | 2024 Q2 |
| Quinn Opportunity Partners LLC | 178.4k | 0.31% | $5.4M | trimmed -26.6% | 2025 Q3 |
| Walleye Capital LLC | 177.5k | 0.31% | $5.4M | opened | 2026 Q1 |
| Boothbay Fund Management, LLC | 176.1k | 0.31% | $5.4M | trimmed -7.6% | 2025 Q3 |
| Nuveen | 162.9k | 0.28% | $4.9M | added +79.1% | 2024 Q2 |
| Woodline Partners LP | 137.7k | 0.24% | $4.2M | trimmed -37.2% | 2024 Q4 |
| BNY Mellon | 130.7k | 0.23% | $4.0M | added +10.4% | 2020 Q3 |
| Group ONE Trading LLC | 127.1k | 0.22% | $3.9M | opened | 2021 Q1 |
| Charles Schwab Investment Management | 126.0k | 0.22% | $3.8M | added +5.6% | 2023 Q1 |
| PFM Health Sciences, LP | 123.8k | 0.22% | $3.8M | opened | 2026 Q1 |
| Ally Bridge Group (NY) LLC (focused) | 113.9k | 0.20% | $3.5M | opened | 2026 Q1 |
| Marshall Wace | 109.5k | 0.19% | $3.3M | trimmed -10.2% | 2024 Q2 |
| Wellington Management | 108.6k | 0.19% | $3.3M | trimmed -15.3% | 2024 Q4 |
| Jefferies Financial Group INC. | 104.4k | 0.18% | $3.2M | opened | 2026 Q1 |
| Seven Grand Managers, LLC | 100.0k | 0.17% | $3.0M | unchanged | 2025 Q4 |
| Swiss National Bank | 96.8k | 0.17% | $2.9M | opened | 2026 Q1 |
| Adar1 Capital Management, LLC | 90.6k | 0.16% | $2.8M | opened | 2026 Q1 |
| Black Diamond Financial, LLC | 79.1k | 0.14% | $2.4M | unchanged | 2024 Q4 |
Largest 50 of 169 shown; the full ranked, searchable register is at boothcheck.com/holders/CAPR. Related filers are grouped using the filings' own included-manager declarations. Historically, several managers opening new positions in the same quarter said almost nothing about the quarter that followed (59,118 cases since 2013). A filed record, not a forecast. Nothing here is investment advice.