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MRK vs PFE stock comparison

Merck & Co., Inc. vs Pfizer Inc., two Drug Manufacturers stocks. A side-by-side on valuation, growth, margins, returns, and what each price is betting.

Both pharma balance sheets carry real debt, 1.07 debt to equity at Merck and 0.71 at Pfizer, with current ratios near 1.3. The resemblance ends there: Merck earns 19.5% on equity to Pfizer's 8.3%, on net margins of 13.6% and 11.8%. Priced at 35.9 times earnings against 19.1, Merck carries the expectations and Pfizer carries the doubts, along with a 6.9% dividend to Merck's 2.6%. In this sector the yield is usually where the skepticism shows first.

Comparison updated 2026-07-19.

MRK vs PFE: the numbers

MetricMRKPFE
Price$130.21$25.03
Market cap$321.9B$143.4B
SectorDrug ManufacturersDrug Manufacturers
StageMatureMature
Implied growth (priced in)+11.4%-2.9%
P/E36.719.1
P/B7.011.59
P/S4.892.27
EV/EBITDA629.431.3
Revenue growth+2.9%+2.1%
Net margin13.6%11.8%
Return on equity19.4%8.3%
Return on assets6.9%3.6%
FCF yield4.4%6.6%
Dividend yield2.5%6.9%
Debt / equity1.070.71
Current ratio1.301.25
Altman Z (solvency)7.311.88
Piotroski F (quality)6 / 96 / 9
Full MRK report → Full PFE report →
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The stronger value is highlighted per metric where one is strictly better on that single number; it is not an overall verdict on either company. For informational and research purposes only. Not investment advice. Not a recommendation to buy, sell, or hold any security. boothcheck is not a registered investment adviser. Past performance does not guarantee future results.